Sterically Constrained 'Roofed' 2-Thiazolidinones as Excellent Chiral Auxiliaries.
نویسندگان
چکیده
منابع مشابه
Chiral Auxiliaries in Asymmetric Synthesis
Background The use of chiral auxiliaries in the synthesis of enantiomerically pure compounds has found wide application for a variety of reactions over the last three decades. Despite the extensive developments in this area by many academic and industrial research groups, new auxiliary controlled reactions continue to evolve frequently [1]. First objectives in this area have been to develop chi...
متن کاملOptimizing dirhodium(II) tetrakiscarboxylates as chiral NMR auxiliaries.
Thirteen enantiopure paddlewheel-shaped dirhodium(II) tetrakiscarboxylate complexes have been checked for their efficiency in the dirhodium method (differentiation of enantiomers by NMR spectroscopy); six of them are new. Their diastereomeric dispersion effects were studied and compared via so-called key numbers KN. Adducts of each complex were tested with five different test ligands representi...
متن کاملHelicene-Based Chiral Auxiliaries and Chirogenesis
Helicenes are unique helical chromophores possessing advanced and well-controlled spectral and chemical properties owing to their diverse functionalization and defined structures. Specific modification of these molecules by introducing aromatic rings of differing nature and different functional groups results in special chiroptical properties, making them effective chiral auxiliaries and supram...
متن کاملEnglish Auxiliaries as Tense Innections
The standard view of English reduced auxiliaries takes them to be (postlexical) clitics (Kaisse 1983). However, Spencer (1991) puts forward some persuasive arguments that a subset of these forms, the non-syllabic reduced auxiliaries, are actually aaxes (tense innec-tions) rather than clitics, while the syllabic reduced auxiliaries are post-lexical clitics. We accept the logic of Spencer's posit...
متن کاملHighly selective acetate aldol additions using mesityl-substituted chiral auxiliaries.
[reaction: see text] Highly diastereoselective acetate aldol additions using chlorotitanium enolates of mesityl-substituted N-acetyloxazolidinethione and N-acetylthiazolidinethione auxiliaries are reported. These additions proceed in high yields and diastereoselectivities (93:7 to 98:2) for aliphatic, aromatic, and ,-unsaturated aldehydes. Double diastereoselective acetate aldol additions are a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2000
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.48.1541